Assessment of Variation Throughout the Year in the Incidence of Idiopathic Sudden Sensorineural Hearing Loss
Assessment of Variation Throughout the Year in the Incidence of Idiopathic Sudden Sensorineural Hearing Loss
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DOI：
10.1097/mao.0b013e3181c4c2d6
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发表时间：
2010-01-01
影响因子：
2.1
通讯作者：
Selesnick, Samuel H.
中科院分区：
文献类型：
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作者：
Jourdy, Deya N.;Donatelli, Luke A.;Selesnick, Samuel H.
目的：本研究旨在确定特发性突发性感音神经性听力损失（ISSHL）的发病率是否在一年中发生变化。研究设计：本研究是一项回顾性病例回顾。设置：本研究在一家教学医院的三级转诊中心进行。患者：纳入标准是经听力测定数据证实的ISSHL诊断。排除标准为颅内肿瘤、梅尼埃病史、既往耳部手术、头部或颈部化疗或放疗。没有基于年龄的排除标准。97例患者符合这些标准。中位年龄为52岁（范围，26-85岁），有53名（54.6%）女性和44名（45.4%）男性。通过标准统计检验分析计数的不均匀发病率分布和季节变化。结果：总体而言，没有发现不均匀分布或峰值的证据，无论是通过卡方检验（2）（p > 0.1），评估任何不均匀分布，还是通过圆形平均值（p > 0.1），评估季节变化的模式。患者亚组（24/97; 24.7%）报告在ISSHL发作之前或同时经历过上呼吸道感染，没有证据表明全年听力损失发作的分布不均匀，无论是通过chi（2）结论：ISSHL发病率并非呈不均匀分布。
Objective: This study was conducted to determine whether the incidence of idiopathic sudden sensorineural hearing loss (ISSHL) varies throughout the year.Study Design: This study is a retrospective case review.Setting: This study was conducted at a tertiary referral center within a teaching hospital.Patients: Inclusion criteria were a diagnosis of ISSHL confirmed by audiometric data. Exclusion criteria were intracranial neoplasms, a history of Meniere's disease, previous ear procedures, chemotherapy, or radiation therapy to the head or neck. There was no exclusion criterion based on age. Ninety-seven patients met these criteria. The median age was 52 years (range, 26-85 yr), and there were 53 (54.6%) women and 44 (45.4%) men.Main Outcome Measures: Monthly incidence counts were compiled across a 3-year period. Counts were analyzed for uneven incidence distributions and seasonal variation via standard statistical tests.Results: Overall, no evidence was found for an uneven distribution or for a peak either by chi(2) (p > 0.1), which assesses for any uneven distribution, or by the circular mean (p > 0.1), which assesses for a pattern of seasonal variation. In the subset of patients (24 of 97; 24.7%) who reported experiencing an upper respiratory infection before or concurrent with the onset of ISSHL, no evidence was found for an uneven distribution of hearing loss onset throughout the year either by chi(2) (p > 0.1) or by the circular mean (p > 0.1).Conclusion: The results of this study suggest that ISSHL incidence does not display uneven distribution throughout the year.