Consequences of undetected olfactory loss for human chemosensory communication and well-being
Consequences of undetected olfactory loss for human chemosensory communication and well-being
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DOI：
10.1098/rstb.2019.0265
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发表时间：
2020-06-08
影响因子：
6.3
通讯作者：
Hummel, T.
中科院分区：
文献类型：
--
作者：
Oleszkiewicz, A.;Kunkel, F.;Hummel, T.
嗅觉感知对人类化学感觉通信有影响，在更广泛的背景下，它影响幸福。然而，大多数调查嗅觉丧失后果的研究都招募了已经被归类为嗅觉功能障碍并在耳鼻喉科诊所寻求帮助的患者。我们通过区分嗅觉障碍受试者和一组在入组本研究时均宣称嗅觉正常的受试者来重新审视这些发现。在203人的初始样本中，我们发现59人嗅觉受损，4人嗅觉表现不佳，在日常生活中没有用处。有趣的是，我们发现了认知功能的显着组间差异，进一步支持认知和嗅觉表现之间的关系的概念。然而，他们的化学感觉沟通和幸福似乎没有什么不同，与正常的受试者。嗅觉功能受损肯定会对日常生活产生严重影响，但对那些受其困扰并决定寻求治疗的人来说更是如此。在既不抱怨也不寻求耳鼻喉科诊所帮助的受试者中，嗅觉感知有限或没有似乎对他们的社会，认知，情感和健康功能没有重大影响。本文是Theo Murphy会议议题“人类的嗅觉交流”的一部分。
Olfactory perception has implications for human chemosensory communication and in a broader context, it affects well-being. However, most of the studies investigating the consequences of olfactory loss have recruited patients who have already been categorized as having a dysfunctional sense of smell and sought help in an ENT clinic. We revisit these findings by distinguishing subjects with olfactory impairment from a group of subjects who all declared a normal sense of smell when enrolling for this study. In the initial sample of 203 individuals, we found 59 to have impaired olfaction and four with marginal olfactory performance, not useful in daily life. Interestingly, we found a significant between-group difference in cognitive functioning, further supporting the notion of the relationship between cognition and olfactory performance. However, their chemosensory communication and well-being appeared not to be different from subjects with normosmia. Impaired olfactory function certainly has a severe impact on daily life but more so in individuals who are bothered with it and decide to seek treatment. The limited-to-no olfactory perception in the fraction of subjects who neither complain about it nor seek help in ENT clinics does not seem to have a major effect on their social, cognitive, emotional and health functioning. This article is part of the Theo Murphy meeting issue 'Olfactory communication in humans'.