The response of the neuronal activity in the somatosensory cortex after high-intensity intermediate-frequency magnetic field exposure to the spinal cord in rats under anesthesia and waking states
The response of the neuronal activity in the somatosensory cortex after high-intensity intermediate-frequency magnetic field exposure to the spinal cord in rats under anesthesia and waking states
复制标题
大鼠麻醉和清醒状态下脊髓高强度中频磁场照射后体感皮层神经元活动的反应
DOI：
10.1016/j.brainres.2020.147063
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发表时间：
2020
期刊：
影响因子：
2.9
通讯作者：
Satoshi Nakasono
中科院分区：
文献类型：
--
作者：
Atsushi Saito;Keiji Wada;Yukihisa Suzuki;Satoshi Nakasono
随着电力利用水平的提高，在生活环境中利用中频磁场（IF-MF）的新技术越来越受欢迎。然而，在电动汽车或医疗设备的无线电力传输技术（如磁刺激技术）中使用的高强度和突发型中频暴露所引起的生物效应尚未得到很好的了解。在这里，我们开发了一个实验平台，使用大鼠，结合了18 kHz，高强度（最大88 mT），高斯形突发中频-中频暴露系统和体内细胞外记录系统。在本文中，我们旨在报道IF-MF暴露于大鼠脊髓诱导的体感皮层和周围神经纤维区域刺激反应的定性差异。我们还报道了在麻醉或清醒状态下体感觉皮层刺激反应的调节。利用该实验平台，我们成功地检测了IF-MF暴露于脊髓后大鼠体感觉皮层的运动诱发电位或神经元活动。与麻醉状态相比，清醒状态下体感觉皮层的神经元活动增强。另一方面，这些神经元反应不能仅通过中频中频暴露相关的线圈声音来证实。我们的实验结果揭示了中频-中频刺激脊髓的生物学反应和兴奋机制的基本知识。
Novel technologies using the intermediate-frequency magnetic field (IF-MF) in living environments are becoming popular with the advance in electricity utilization. However, the biological effects induced by the high-intensity and burst-type IF-MF exposure used in the wireless power transfer technologies for electric vehicles or medical devices, such as the magnetic stimulation techniques, are not well understood. Here, we developed an experimental platform using rats, that combined an 18 kHz, high-intensity (Max. 88 mT), Gaussian-shaped burst IF-MF exposure system with an in vivo extracellular recording system. In this paper, we aimed to report the qualitative differences in stimulus responses in the regions of the somatosensory cortex and peripheral nerve fibers that were induced by the IF-MF exposure to the rat spinal cord. We also report the modulation of the stimulus responses in the somatosensory cortex under anesthesia or waking states. Using this experimental platform, we succeeded in the detection of the motor evoked potentials or the neuronal activity in the somatosensory cortex that was induced by the IF-MF exposure to the spinal cord in rats. Compared to the state of anesthesia, the neuronal activities in the somatosensory cortex was enhanced during the waking state. On the other hand, these neuronal responses could not be confirmed by the IF-MF exposure-related coil sound only. Our experimental results indicated the basic knowledge of the biological responses and excitation mechanisms of the spinal cord stimulation by the IF-MF exposure.
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影响因子：
7.7
作者：
Li B;Virtanen JP;Oeltermann A;Schwarz C;Giese MA;Ziemann U;Benali A
通讯作者：
Benali A
影响因子：
3.8
作者：
Weinberg, Irving N.;Stepanov, Pavel Y.;Reilly, J. Patrick
通讯作者：
Reilly, J. Patrick
异氟醚对运动诱发电位和F波影响的比较
影响因子：
8.8
作者：
Henry H. Zhou;Ching Zhu
通讯作者：
Ching Zhu
脊髓电磁刺激结合神经营养蛋白 NT-3 的转基因递送和运动：脊髓挫伤的新型联合疗法。
影响因子：
2.5
作者：
Hayk A. Petrosyan;Valentina Alessi;Arsen Hunanyan;S. Sisto;V. Arvanian
通讯作者：
V. Arvanian
基于组lasso的多层区域分割提取空间异质性
DOI：
--
发表时间：
2021
期刊：
地理情報システム学会 学術研究発表大会講演集
影响因子：
--
作者：
竹本 一至;井上 亮
通讯作者：
井上 亮