Association between viral seasonality and meteorological factors
Association between viral seasonality and meteorological factors
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DOI：
10.1038/s41598-018-37481-y
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发表时间：
2019-01-30
影响因子：
4.6
通讯作者：
Ramalingam, Sandeep
中科院分区：
文献类型：
--
作者：
Price, Rory Henry Macgregor;Graham, Catriona;Ramalingam, Sandeep
许多病毒可引起上呼吸道感染。它们通常先于严重的下呼吸道感染。每种病毒都有季节性模式，在不同的季节出现活动高峰。我们研究了来自苏格兰爱丁堡的每日当地气象数据（温度、相对湿度、“湿度范围”和露点）对病毒传播季节变化的影响。我们从2009年至2015年间检测的52060份呼吸道样本中确定了鼻病毒、腺病毒、甲型和乙型流感病毒、人副流感病毒1-3 （HPIV）、呼吸道合胞病毒（RSV）和人偏肺病毒（HMPV）的季节性，然后通过广义线性模型证实了这一点。我们还研究了气象因素与病毒季节性的关系。全年都存在非包膜病毒。经logistic回归分析，腺病毒、流感病毒A、B、RSV和HMPV偏好低温；RSV和甲型流感病毒喜欢狭窄的“湿度范围”，而HPIV 3型喜欢湿度较低的季节。特定气象因素的变化（即增加或减少）与一年中某些时间特定病毒活动的增加有关。
Numerous viruses can cause upper respiratory tract infections. They often precede serious lower respiratory tract infections. Each virus has a seasonal pattern, with peaks in activity in different seasons. We examined the effects of daily local meteorological data (temperature, relative humidity, "humidityrange" and dew point) from Edinburgh, Scotland on the seasonal variations in viral transmission. We identified the seasonality of rhinovirus, adenovirus, influenza A and B viruses, human parainfluenza viruses 1-3 (HPIV), respiratory syncytial virus (RSV) and human metapneumovirus (HMPV) from the 52060 respiratory samples tested between 2009 and 2015 and then confirmed the same by a generalised linear model. We also investigated the relationship between meteorological factors and viral seasonality. Non-enveloped viruses were present throughout the year. Following logistic regression adenovirus, influenza viruses A, B, RSV and HMPV preferred low temperatures; RSV and influenza A virus preferred a narrow "humidity-range" and HPIV type 3 preferred the season with lower humidity. A change (i.e. increase or decrease) in specific meteorological factors is associated with an increase in activity of specific viruses at certain times of the year.