Contragestion and other clinical applications of RU 486, an antiprogesterone at the receptor.
Contragestion and other clinical applications of RU 486, an antiprogesterone at the receptor.
复制标题
DOI：
10.1097/00006254-199003000-00019
复制
发表时间：
1990-03
期刊：
影响因子：
56.9
通讯作者：
E. Baulieu
中科院分区：
文献类型：
--
作者：
E. Baulieu
RU 486是一种对孕酮受体具有高亲和力的类固醇，是第一种有效的抗孕酮药物。它已被成功地用作早期妊娠中断的医学替代品，并且在医学以及生物化学和病理生理学内分泌研究中也有其他潜在的应用。
RU 486, a steroid with high affinity for the progesterone receptor, is the first available active antiprogesterone. It has been used successfully as a medical alternative for early pregnancy interruption, and it also has other potential applications in medicine and for biochemical and pathophysiological endocrine research.