Functional imaging of retinal photoreceptors and inner neurons using stimulus-evoked intrinsic optical signals.
Functional imaging of retinal photoreceptors and inner neurons using stimulus-evoked intrinsic optical signals.
复制标题
使用刺激诱发的内在光信号对视网膜感光器和内部神经元进行功能成像。
DOI：
10.1007/978-1-61779-848-1_20
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发表时间：
2012
期刊：
影响因子：
--
通讯作者：
Li,Yi-Chao
中科院分区：
文献类型：
--
作者：
Yao,Xin-Cheng;Li,Yi-Chao
Retinal development is a dynamic process both anatomically and functionally. High-resolution imaging and dynamic monitoring of photoreceptors and inner neurons can provide important information regarding the structure and function of the developing retina. In this chapter, we describe intrinsic optical signal (IOS) imaging as a high spatiotemporal resolution method for functional study of living retinal tissues. IOS imaging is based on near infrared (NIR) light detection of stimulus-evoked transient change of inherent optical characteristics of the cells. With no requirement for exogenous biomarkers, IOS imaging is totally noninvasive for functional mapping of stimulus-evoked spatiotemporal dynamics of the photoreceptors and inner retinal neurons.
