Intracranial mass lesions: Sequential thallium and gallium scintigraphy in patients with AIDS
Intracranial mass lesions: Sequential thallium and gallium scintigraphy in patients with AIDS
复制标题
DOI：
10.1148/radiology.211.2.r99ma37507
复制
发表时间：
1999-05-01
期刊：
影响因子：
19.7
通讯作者：
Cooley, TP
中科院分区：
文献类型：
--
作者：
Lee, VW;Antonacci, V;Cooley, TP
目得：目的：确定铊和镓序贯脑血管造影鉴别颅内肿瘤的有效性（淋巴瘤和神经胶质瘤）与患者中其他非恶性颅内肿块病变的关系;;患有获得性免疫缺陷综合征（艾滋病）。材料和方法：作者回顾性分析了40例人类免疫缺陷病毒（HIV）感染者的临床资料从1991年10月到1997年11月接受铊和镓扫描以评估颅内肿块病变。有一个明确的最终诊断的性质的肿块病变在这些案件中的21个。结果：根据铊、镓扫描结果，将患者分为三组，分别为10例、10例、10例、10例。A组包括13名铊、镓扫描呈阳性的患者（11名患有脑肿瘤[淋巴瘤和神经胶质瘤]，2名患有进行性多灶性白质脑病[PML]）。B组包括5例颅内感染（结核、隐球菌、细菌），铊阴性，镓阳性扫描。C组包括3例患者（1例PML和2例梗死），铊阴性，镓阴性扫描。所有淋巴瘤患者均为A组。铊阳性、镓阳性模式对颅内恶性肿瘤的敏感性和特异性分别为100%和80%，respectively.CONCLUSION：铊和镓序列扫描有助于区分肿瘤与非恶性颅内肿块病变，并可能有助于区分感染与PML或梗死。
PURPOSE: TO determine the efficacy of sequential thallium and gallium scintigraphy to differentiate intracranial neoplasms (lymphoma and glioma) from other nonmalignant intracranial mass lesions among patients;; with acquired immunodeficiency syndrome (AIDS).MATERIALS AND METHODS: The authors reviewed the cases of 40 patients with human immunodeficiency virus (HIV) who underwent thallium and gallium scanning to evaluate intracranial mass lesions from October 1991 through November 1997. There was a definitive final diagnosis of the nature of the mass lesions in 21 of these cases. In these 21 cases, the scintigraphic patterns were reviewed and were compared with the final diagnosis.RESULTS: On the basis of results at thallium and gallium scanning, the patients were divided into three groups. Group A included 13 patients (11 with brain tumors [lymphomas and gliomas] and two with progressive multifocal leukoencephalopathy [PML]) with thallium-positive, gallium-positive scans. Group B included five patients with intracranial infections (tuberculosis, Cryptococcus, bacteria) with thallium-negative, gallium-positive scans. Group C included three patients (one with PML and two with infarcts) with thallium-negative, gallium-negative scans. All patients with lymphomas were in group A. The sensitivity and specificity of the thallium-positive, gallium-positive pattern for intracranial malignancy were 100% and 80%, respectively.CONCLUSION: Sequential thallium and gallium scanning helped differentiate tumors from nonmalignant intracranial mass lesions and may help differentiate infections from PML or infarcts.