The obstetric antiphospholipid syndrome
The obstetric antiphospholipid syndrome
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DOI：
10.1016/j.jri.2006.12.003
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发表时间：
2008-01-01
影响因子：
3.4
通讯作者：
de Grootb, Ph. G.
中科院分区：
文献类型：
--
作者：
Derksen, R. H. W. M.;de Grootb, Ph. G.
抗磷脂综合征是指循环中持续存在抗磷脂抗体与血栓栓塞事件、（复发性）妊娠丢失或两者同时存在的现象。患有该综合征的妇女怀孕应被视为并发症的高风险。包括密切随访和药物治疗的最佳管理可导致约70-80%的活产。除了综合征的实验室诊断和病理生理学，本次审查将集中在怀孕期间的治疗。(c)2007爱思唯尔爱尔兰有限公司保留所有权利。
The association of persistent presence of circulating antiphospholipid antibodies and thromboembolic events, (recurrent) pregnancy loss or both is termed antiphospholipid syndrome. Pregnancies in women with the syndrome should be regarded as at high-risk for complications. Optimal management consisting of close follow-up and pharmacological treatment can result in about 70-80% live births. Apart from the laboratory diagnosis of the syndrome and pathophysiology, this review will focus on treatment during pregnancy. (c) 2007 Elsevier Ireland Ltd. All rights reserved.