DETECTION OF LEUKOTRIENE-C4-LIKE IMMUNOREACTIVITY IN TEAR FLUID FROM SUBJECTS CHALLENGED WITH SPECIFIC ALLERGEN
DETECTION OF LEUKOTRIENE-C4-LIKE IMMUNOREACTIVITY IN TEAR FLUID FROM SUBJECTS CHALLENGED WITH SPECIFIC ALLERGEN
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DOI：
10.1016/0090-6980(84)90196-5
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发表时间：
1984-01-01
影响因子：
2.9
通讯作者：
TAUDORF, E
中科院分区：
文献类型：
--
作者：
BISGAARD, H;FORDHUTCHINSON, AW;TAUDORF, E
泪液从过敏受试者的控制眼睛和眼睛的挑战与特定的过敏原和水平的白三烯[LT] C4-免疫反应性测定放射免疫法。释放的LT的正式鉴定是不可能的，但在变应原激发的泪液中LTC 4免疫反应性物质的水平（4.9 . ±. 2.3 ng/ml，n = 9）显著高于对照泪液（0.07 ± 0.01）。0.06 ng/ml，n = 9）。LT是过敏性慢反应物质的生物活性物质，在人体过敏反应中可释放。
Tear fluid was obtained from allergic subjects from control eyes and eyes challenged with specific allergen and levels of leukotriene [LT] C4-immunoreactivity determined by radioimmunoassay. Formal identification of the LT released was not possible but the levels of LTC4-immunoreactive material in allergen-challenged tear fluid (4.9 .+-. 2.3 ng/ml, n = 9) were significantly higher (P < 0.01) than those in control tear fluid (0.07 .+-. 0.06 ng/ml, n = 9). LT, which account for the biological activity of slow reacting substance of anaphylaxis, may be released in allergic reactions in vivo in man.