Within-flock transmission of H7N1 highly pathogenic avian influenza virus in turkeys during the Italian epidemic in 1999-2000
Within-flock transmission of H7N1 highly pathogenic avian influenza virus in turkeys during the Italian epidemic in 1999-2000
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DOI：
10.1016/j.prevetmed.2010.04.006
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发表时间：
2010-07-01
影响因子：
2.6
通讯作者：
Busani, Luca
中科院分区：
文献类型：
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作者：
Bos, Marian E. H.;Nielen, Mirjam;Busani, Luca
高致病性禽流感(HPAI)病毒在病毒株和宿主种之间表现出不同的疾病动态，因此流行场数据非常有价值。这项研究使用了1999-2000年影响意大利北部的HPAI H7N1疫情的现场数据。现场死亡数据被反算成S-I格式，以估计传播率参数β，该参数表示每只感染禽类每时间单位感染的禽类数量。假设禽类感染期为2天，所有禽类在此感染期后都将死亡。HPAI H7N1病毒在火鸡中传播的估计贝塔系数为1.43(95%可信区间：1.17-1.74)。农场风险因素，如火鸡群大小和年龄，不影响估计的传播率参数。(C)2010爱思唯尔B.V.保留所有权利。
Highly pathogenic avian influenza (HPAI) viruses show different disease dynamics between virus strains and host species, and therefore epidemic field data are very valuable. This study used field data of the HPAI H7N1 epidemic which affected Northern Italy in 1999-2000. Field mortality data was back-calculated into a S-I-format to estimate the transmission rate parameter beta, indicating the number of birds infected per infectious bird per time unit. The bird-infectious period was assumed to be 2 days, and all birds were assumed to die after this infectious period. The estimated beta for HPAI H7N1 virus transmission in turkeys was 1.43 (95% CI: 1.17-1.74). Farm risk factors such as flock size and age of the turkeys did not influence the estimated transmission rate parameter. (C) 2010 Elsevier B.V. All rights reserved.