Cough, pain and dyspnoea: Similarities and differences

Cough, pain and dyspnoea: Similarities and differences
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DOI:
10.1016/j.pupt.2006.12.005
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发表时间:
2007-01-01
影响因子:
3.2
通讯作者:
Banzett, Robert B.
Banzett, Robert B.
中科院分区:
医学3区
文献类型:
--
作者:
Gracely, Richard H.;Undem, Bradley J.;Banzett, Robert B.

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疼痛、呼吸困难和咳嗽这三种常见症状具有一些共同的重要特征。我们认为,在它们之间进行类比可能是有启发性的,可能会提出新的研究途径。这些症状中的每一个都可能非常不舒服,并可能严重降低生活质量。症状咳嗽通常比症状咳嗽更突出,但两者对患者都很重要(前者可能更受附近人的关注)。在过去的几十年里,疼痛研究的进展为呼吸困难的新研究指明了方向;它们可以作为咳嗽冲动感知的心理物理学研究的模型,并为理解传入通路的中枢和外周敏化提供模型。我们在这里简要回顾传入和中枢通路和疼痛,呼吸困难和咳嗽冲动的心理物理学。(c)2007爱思唯尔有限公司保留所有权利。
The three common symptoms, pain, dyspnoea and cough, share some important features. We felt that the analogies to be made among them could be instructive, possibly suggesting new avenues of research. Each of these symptoms can be profoundly uncomfortable, and can profoundly degrade quality of life. The sign, cough, is often given more prominence than the symptom, urge to cough, but both are important to the patient (the former may be of more concern to nearby people). Advances in pain research over the last several decades have pointed the way to new studies of dyspnoca; they may serve as a model for the psychophysical study of the perception of urge to cough, as well as providing models for understanding both central and peripheral sensitization of the afferent pathway. We briefly review here the afferent and central pathways and psychophysics of pain, dyspnoea and urge to cough. (c) 2007 Elsevier Ltd. All rights reserved.