Unilateral acute maculopathy related to hand, foot, and mouth disease: OCT and fluorescein angiography findings of a very rare disease
Unilateral acute maculopathy related to hand, foot, and mouth disease: OCT and fluorescein angiography findings of a very rare disease
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DOI：
10.5301/ejo.5000288
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发表时间：
2014-01-01
影响因子：
1.7
通讯作者：
Ozmert, Emin
中科院分区：
文献类型：
--
作者：
Demirel, Sibel;Batioglu, Figen;Ozmert, Emin
目的：手足口病是一种肠道病毒传染病，主要发生在儿童身上，以水疱性掌跖疹和糜烂性口炎为特征。有极少数的情况下，单侧急性特发性黄斑病变与手，足，口感染。我们描述了一例发生在发病后几天的单侧外视网膜炎。方法：一名30岁的男子，视力下降，在他的右眼进行了完整的眼科检查，包括荧光素血管造影和光谱光学相干断层扫描。结果：眼底荧光素血管造影表现出斑驳的高荧光在早期阶段和泄漏在晚期阶段。光谱域光学相干断层扫描显示视网膜下液体提示浆液性脱离，也显示轻度视网膜内囊性变化。1周内液体消失，黄斑中心有视网膜色素上皮细胞改变。结论：虽然这种疾病是一种病毒感染，伴有可逆性症状，但这种情况表明，它可以解决轻度视力下降，这种疾病应考虑在急性中心性浆液性脉络膜视网膜病变的鉴别诊断。
Purpose: Hand, foot, and mouth disease is a contagious enteroviral infection occurring primarily in children and characterized by vesicular palmoplantar eruptions and erosive stomatitis. There are very few cases of unilateral acute idiopathic maculopathy associated with hand, foot, and mouth infection. We described a case with unilateral outer retinitis occurring a few days after the onset of disease.Methods: A 30-year-old man with reduced vision in his right eye underwent complete ophthalmologic examination including fluorescein angiography and spectral optical coherence tomography.Results: Fundus fluorescein angiography demonstrated mottled hyperfluorescence in the early phase and leakage in the late phase. Spectral domain optical coherence tomography revealed subretinal fluid suggesting a serous detachment and also showed mild intraretinal cystic changes. The fluid disappeared in 1 week with some retinal pigment epithelium changes in the center of the macula.Conclusions: Although this disease is a viral infection associated with reversible symptoms, this case suggests that it can resolve with mild visual loss, and the disease should be considered in the differential diagnosis of acute central serous chorioretinopathy.