Detection of the SARS-CoV-2 spike protein in saliva with Shrinky-Dink© electrodes.
Detection of the SARS-CoV-2 spike protein in saliva with Shrinky-Dink© electrodes.
复制标题
使用 Shrinky-Dink© 电极检测唾液中的 SARS-CoV-2 刺突蛋白。
DOI:
10.1039/d1ay00041a
复制
发表时间:
2021
期刊:
影响因子:
--
通讯作者:
Khine,Michelle
中科院分区:
文献类型:
--
作者:
Zakashansky,JuliaA;Imamura,AmandaH;Salgado2nd,DarwinF;RomeroMercieca,HeatherC;Aguas,RaphaelFL;Lao,AngelouM;Pariser,Joseph;Arroyo-Currás,Netzahualcóyotl;Khine,Michelle
Using the children's toy, Shrinky-Dink©, we present an aptamer-based electrochemical (E-AB) assay that recognizes the spike protein of SARS-CoV-2 in saliva for viral infection detection. The low-cost electrodes are implementable at population scale and demonstrate detection down to 1 ag mL−1 of the S1 subunit of the spike protein.