Maternal weight gain in pregnancy and risk of obesity among offspring: a systematic review.
Maternal weight gain in pregnancy and risk of obesity among offspring: a systematic review.
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DOI：
10.1155/2014/524939
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发表时间：
2014
影响因子：
3.3
通讯作者：
Liu J
中科院分区：
文献类型：
--
作者：
Lau EY;Liu J;Archer E;McDonald SM;Liu J
目标.系统回顾前瞻性和回顾性队列研究中关于妊娠期体重增加（GWG）与子代体重相关性的证据。方法.检索了PubMed、Web of Science、CINAHL和Academic Search Premiere电子数据库，检索时间从开始到2013年3月18日。纳入的研究（n = 23）是英文文章，研究了GWG与2至18.9岁子女的体重指数（BMI）和/或超重状态的独立关联。两位作者独立提取数据并评估纳入研究的方法学质量。结果来自队列研究的证据支持，总GWG和超过医学研究所的母亲体重增加建议与较高的BMI z评分和后代超重或肥胖的风险增加相关。妊娠早期和中期GWG发生率高的证据提示。此外，GWG和净GWG不足与后代体重结局相关的证据不足以得出结论。结论.这些发现表明GWG是儿童肥胖的潜在危险因素。然而，由于GWG的测量问题和共同家族特征的潜在混杂效应（即，遗传学和母亲和孩子的生活方式因素）。
Objectives. To systematically review the evidence from prospective and retrospective cohort studies on the association between gestational weight gain (GWG) and offspring's body weight. Methods. Electronic databases PubMed, Web of Science, CINAHL, and Academic Search Premiere were searched from inception through March 18, 2013. Included studies (n = 23) were English articles that examined the independent associations of GWG with body mass index (BMI) and/or overweight status in the offspring aged 2 to 18.9 years. Two authors independently extracted the data and assessed methodological quality of the included studies. Results. Evidence from cohort studies supports that total GWG and exceeding the Institute of Medicine maternal weight gain recommendation were associated with higher BMI z-score and elevated risk of overweight or obesity in offspring. The evidence of high rate of GWG during early- and mid-pregnancy is suggestive. Additionally, the evidence on inadequate GWG and net GWG in relation to body weight outcomes in offspring is insufficient to draw conclusions. Conclusions. These findings suggest that GWG is a potential risk factor for childhood obesity. However, findings should be interpreted with caution due to measurement issues of GWG and potential confounding effects of shared familial characteristics (i.e., genetics and maternal and child's lifestyle factors).