PAROXYSMAL DYSARTHRIA AND ATAXIA IN MULTIPLE SCLEROSIS - A REPORT OF 2 UNUSUAL CASES
PAROXYSMAL DYSARTHRIA AND ATAXIA IN MULTIPLE SCLEROSIS - A REPORT OF 2 UNUSUAL CASES
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DOI：
10.1212/wnl.9.4.211
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发表时间：
1959-01-01
期刊：
影响因子：
9.9
通讯作者：
WALTERS, AM
中科院分区：
文献类型：
--
作者：
ANDERMANN, F;COSGROVE, JBR;WALTERS, AM
本文报告2例多发性硬化患者的阵发性构音障碍和共济失调。这些发生在持续10-20秒的短暂攻击中。突然发作和停止，并在数月内复发，最终完全消失。各种形式的语言障碍描述多发性硬化症进行审查。文献检索未能发现任何类似的阵发性构音障碍病例。鉴别诊断进行了讨论，并提出的原因，它表明，攻击可能起源于位于小脑或其连接在脑干的干扰。这些攻击在多发性硬化症的发病机制的含义进行了简要讨论。
Paroxysmal dysarthria and ataxia in 2 patients with multiple sclerosis are reported. These occurred in brief attacks lasting 10-20 sec. with sudden onset and cessation, and recurred over a period of months, eventually disappearing completely. The various forms of disturbance of speech described in multiple sclerosis are reviewed. A search of the literature has failed to reveal any similar cases of paroxysmal dysarthria. The differential diagnosis is discussed and, for the reasons presented, it is suggested that the attacks may originate in a disturbance situated in the cerebellum or in its connections in the brain stem. The implication of these attacks in the pathogenesis of multiple sclerosis is briefly discussed.