Copper-Catalyzed Si-B Bond Activation in the Nucleophilic Substitution of Primary Aliphatic Triflates
Copper-Catalyzed Si-B Bond Activation in the Nucleophilic Substitution of Primary Aliphatic Triflates
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DOI：
10.1055/s-0035-1561407
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发表时间：
2016-05-01
期刊：
影响因子：
2
通讯作者：
Oestreich, Martin
中科院分区：
文献类型：
--
作者：
Scharfbier, Jonas;Oestreich, Martin
A method for the nucleophilic displacement of the triflate leaving group attached to terminally functionalized alkyl groups with nucleophilic silicon is reported. Copper catalysis is used to release the silicon nucleophile from Suginome's Si-B reagent. The functional group tolerance is excellent, and halide leaving groups do also work with the same protocol.
