Removal of oestrogens and oestrogen mimics from the environment.
Removal of oestrogens and oestrogen mimics from the environment.
复制标题
从环境中去除雌激素和雌激素模拟物。
DOI：
10.1042/bst0260675
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发表时间：
1998
影响因子：
3.9
通讯作者：
H. Wiseman
中科院分区：
文献类型：
--
作者：
T. Ridgway;H. Wiseman
目前存在关于男性生殖健康可能下降的争议[l]。然而，明确的是，雌激素、雌激素模拟物和其他内分泌干扰物质已被证明对水生野生动物造成重大不利影响[2]。有害的雌激素污染物/毒物包括天然甾醇（最显著的是17 P-雌激素）和合成的雌激素模拟物（异雌激素），例如邻苯二甲酸酯和烷基酚[3]。正是这种显示雌激素活性的化合物的多样性导致在环境、食品包装和食品中发现雌激素物质。如果要保护男性生殖健康，可能必须考虑人类接触雌激素的总量。因此，有必要结合各种方法来减少总接触量：防止使用某些类别的雌激素化合物;通过过滤或生物修复去除有害化学品，并将其改造为非活性形式。这里考虑的技术可以减少雌激素的暴露，从活性炭过滤到植物的基因工程。
There is at present controversy over a potential decline in male reproductive health [l]. What is clear, however, is that oestrogens, oestrogen mimics and other endocrine disrupting substances, have been demonstrated to cause significant adverse effects on aquatic wildlife [2]. The offending oestrogenic pollutants/toxicants include natural sterols, most significantly 17P-oestradio1, and synthetic oestrogenic mimics (xenoestrogens), for example, phthalates and alkyphenols [3]. It is this diverse range of compounds showing oestrogenic activity that results in oestrogenic substances being found in the environment, in food packaging and in foodstuffs. If male reproductive health is to be protected it is likely that total human exposure to oestrogens will have to be considered. A combination of approaches may then be necessary to reduce total exposure: the prevention of use of some classes of oestrogenic compound; the removal by filtration or bioremediation of offending chemicals, and modification to inactive forms. The technology which could enable reduced oestrogen exposure, ranging from activated-carbon filtration to the genetic engineering of plants, is considered here.