Changes in axial length and choroidal thickness after intraocular pressure reduction resulting from trabeculectomy.
Changes in axial length and choroidal thickness after intraocular pressure reduction resulting from trabeculectomy.
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DOI：
10.2147/opth.s44884
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发表时间：
2013
期刊：
影响因子：
--
通讯作者：
Otori Y
中科院分区：
文献类型：
--
作者：
Usui S;Ikuno Y;Uematsu S;Morimoto Y;Yasuno Y;Otori Y
目的观察小梁切除术后眼轴长度和脉络膜厚度的变化。入组了14例80岁以下的青光眼患者。使用原型高穿透光学相干断层扫描（OCT）对脉络膜进行成像，并测量厚度。在小梁切除术前1天和术后6天下午3点测量眼轴长度、脉络膜厚度和眼内压（IOP）。在中心凹和其他四个位置（距视神经乳头中心上级、颞侧、下侧和鼻侧2 mm）测量脉络膜厚度。接受小梁切除术的眼的IOP和眼轴长度显著降低（IOP P < 0.0001;眼轴长度比较P < 0.001）。与术前相比，接受小梁切除术的眼睛的平均脉络膜厚度显著增加（中央凹P < 0.0001;视盘周围四个位置P < 0.01）。眼压的平均变化幅度与眼轴长度的平均变化幅度呈正相关，但与接受小梁切除术的中心凹脉络膜厚度的平均变化幅度不相关。术后眼轴长度和中心凹下脉络膜厚度之和较术前明显降低（P < 0.05）。术后早期眼轴长度缩短，脉络膜增厚，眼轴长度与中心凹下脉络膜厚度之和随眼压降低而减小。
To evaluate changes in axial length and choroidal thickness after trabeculectomy. Fourteen patients under 80 years of age with glaucoma, were enrolled. The choroid was imaged using prototypical high-penetration optic coherence tomography (OCT) and the thickness was measured. Axial length, choroidal thickness, and intraocular pressure (IOP) were measured bilaterally at 3 pm 1 day before and 6 days after trabeculectomy. The choroidal thickness was measured at the fovea and four other locations (2 mm superior, temporal, inferior, and nasal to the center of the optic nerve head). The IOP and axial length significantly decreased in eyes that underwent trabeculectomy (P < 0.0001 for the IOP; P < 0.001 for axial length comparisons). The mean choroidal thicknesses significantly increased in eyes that underwent trabeculectomy compared to preoperatively (P < 0.0001 for the fovea; P < 0.01 for four locations around the optic disc). The mean magnitude of change in IOP was correlated positively with the mean magnitude of change in axial length, but not correlated with the mean magnitude of change in choroidal thickness at the fovea that underwent trabeculectomy. The sum of the axial length and subfoveal choroidal thickness in eyes decreased significantly postoperatively (P < 0.05). The axial length shortened, the choroid thickened, and the sum of the axial length and subfoveal choroidal thickness decreased with IOP reduction early after trabeculectomy.