Percutaneous Mitral Valve Repair
Percutaneous Mitral Valve Repair
复制标题
经皮二尖瓣修复术
DOI：
10.1007/s11886-013-0443-6
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发表时间：
2013
影响因子：
3.7
通讯作者：
T. Feldman
中科院分区：
文献类型：
--
作者：
A. Young;T. Feldman
在过去的十年中，临床上重要的二尖瓣返流（MR）的非手术治疗发生了巨大的变化。经皮二尖瓣修复术的最新研究表明，微创手术是安全的，对选定的患者有效。MitraClip已被广泛研究。通过经中隔-经血管入路将二尖瓣夹系统连接到二尖瓣瓣叶的中间扇形。该器械以缘对缘经皮修复技术对合瓣叶，可减少二尖瓣返流，改善功能状态，并改善左心室重塑。受益最大的亚组包括年龄较大、左心室功能较差和功能性二尖瓣返流的患者，被认为是外科瓣膜置换术的高风险患者。正在研究的其他新型经皮二尖瓣治疗包括间接和直接瓣环成形术和心室重塑器械。
Nonsurgical treatment of clinically important mitral regurgitation (MR) has evolved tremendously over the past decade. Recent studies of percutaneous mitral valve repair procedures have shown that less invasive procedures are safe and can be effective in selected patients. MitraClip has been studied most extensively. The MitraClip is attached to the middle scallop of the mitral leaflets by a transseptal-transvascular approach. The device approximates the leaflets in an edge-to-edge percutaneous repair technique that diminishes MR, improves functional status, and improves left ventricular remodeling. The subgroup that has the most benefit includes patients with older age, poorer left ventricular function, and functional MR and is considered high risk for surgical valve replacement. Other novel percutaneous mitral valve therapies under investigation include indirect and direct annuloplasty, and ventricular remodeling devices.