THE CARDIAC OUTPUT IN PATIENTS WITH CHRONIC ANEMIA AS MEASURED BY THE TECHNIQUE OF RIGHT ATRIAL CATHETERIZATION
THE CARDIAC OUTPUT IN PATIENTS WITH CHRONIC ANEMIA AS MEASURED BY THE TECHNIQUE OF RIGHT ATRIAL CATHETERIZATION
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DOI：
10.1172/jci101610
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发表时间：
1945-01-01
影响因子：
15.9
通讯作者：
STEAD, EA
中科院分区：
文献类型：
--
作者：
BRANNON, ES;MERRILL, AJ;STEAD, EA
方法采用直接菲克原理测定心输出量。右心房混合静脉血样本和心房压力测量由内置心房导管通过肘前静脉进入静脉系统（1,2）。氧气消耗是通过分析2分钟的过期空气样本来确定的，使用霍尔丹法。代谢率被记录为偏离预期基础代谢的百分比。采用Van Slyke和Neill(3)的方法测定血液中的氧含量。取右肋-软骨第4连接点下方5 cm处作为基准点，读取心房压。采用Hamilton法光学记录股动脉动脉压(4)。平均动脉压是通过追踪下方区域的平面积分来测量的。外围电阻计算公式为
METHODS The cardiac output was measured by the utilization of the direct Fick principle. Samples of mixed venous blood from the right atrium and measurements of atrial pressure were obtained from an inlying atrial catheter, introduced into the venous system through the ante-cubital vein (1, 2). The oxygen consumption was de-termined by the analysis of a 2-minute sample of expired air, using the method of Haldane. The metabolic rate was recorded as the percentage of deviation from the expected basal metabolism. The oxygen content of the blood was measured by the method of Van Slyke and Neill (3). A point 5 cm. below the 4th right costo-chondral junction was usedas the reference point in reading the atrial pressure. The arterial pressure in the femoral artery was recorded optically by the method of Hamilton (4). The mean arterial pressure wasmeasured by planimetric integration of the area beneath the tracing. The peripheral resistance was calculated by