A ONE-STEP PROCEDURE FOR PREPARATION OF TERTIARY ALPHA-KETOLS FROM CORRESPONDING KETONES
A ONE-STEP PROCEDURE FOR PREPARATION OF TERTIARY ALPHA-KETOLS FROM CORRESPONDING KETONES
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DOI：
10.1021/jo01272a055
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发表时间：
1968-01-01
影响因子：
3.6
通讯作者：
GNOJ, O
中科院分区：
文献类型：
--
作者：
GARDNER, JN;CARLON, FE;GNOJ, O
17 α-氢过氧官能团的引入是通过在相应的α-烷基醇中的α-醇盐存在下用氧处理孕烷-20-酮来完成的，分离后，将氢过氧化物还原成醇，在乙酸中的锌粉是优选的试剂。
The introduction of the 17a-hydroperoxy function was accomplished by treatment of the preg-nan-20-one with oxygen in the presence of f-alkoxide in the corresponding f-alkyl alcohol, and, after isolation, the hydroperoxide was reduced to the alcohol, zinc dust in acetic acid being the preferred reagent.