Chemical constituents from the peels of Citrus sudachi

Chemical constituents from the peels of Citrus sudachi
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DOI:
10.1021/np060217s
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发表时间:
2006-08-25
影响因子:
5.1
通讯作者:
Higuti, Tomihiko
Higuti, Tomihiko
中科院分区:
生物学2区
文献类型:
--
作者:
Nakagawa, Hiroyuki;Takaishi, Yoshihisa;Higuti, Tomihiko

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从水柑果皮中提取甲醇,得到5个新化合物(1-5)和27个已知化合物。根据光谱证据对其结构进行了分析。其中几种化合物对耐甲氧西林金黄色葡萄球菌和幽门螺杆菌的抑菌活性测定表明,苏达奇丁(6)和3′-去甲氧基苏达奇丁(7)的抑菌活性最高。
A methanol extract of the peels of Citrus sudachi gave five new compounds (1-5) and 27 known compounds. The structures were elucidated on the basis of spectroscopic evidence. Several of these compounds were assayed for antimicrobial activity against methicillin-resistant Staphylococcus aureus and Helicobacter pylori, and sudachitin ( 6) and 3'-demethoxysudachitin (7) were the most active.