A NEW, PALLADIUM-CATALYZED SYNTHESIS OF AROMATIC MERCAPTURIC ACID-DERIVATIVES

A NEW, PALLADIUM-CATALYZED SYNTHESIS OF AROMATIC MERCAPTURIC ACID-DERIVATIVES
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DOI:
10.1016/0040-4039(95)00677-5
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发表时间:
1995-06-05
影响因子:
1.8
通讯作者:
ORTAR, G
ORTAR, G
中科院分区:
化学4区
文献类型:
--
作者:
CIATTINI, PG;MORERA, E;ORTAR, G

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N-乙酰基-L-半胱氨酸甲酯(1)在Pd(2)、dba(3)和Dppf原位制备的钯催化剂的催化下,在温和的条件下与芳基碘2反应,以中等到较好的产率得到S-芳基衍生物3。
N-Acetyl-L-cysteine methyl ester (1) reacts under mild conditions with aryl iodides 2 in the presence of a palladium catalyst prepared in situ from Pd(2)dba(3) and dppf to give S-aryl derivatives 3 in moderate to good yields.