Changes in tibiofemoral forces due to variations in muscle activity during walking.

Changes in tibiofemoral forces due to variations in muscle activity during walking.
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DOI:
10.1002/jor.22601
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发表时间:
2014-06
影响因子:
2.8
通讯作者:
Delp, Scott L.
Delp, Scott L.
中科院分区:
医学3区
文献类型:
--
作者:
DeMers, Matthew S.;Pal, Saikat;Delp, Scott L.

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行走时,肌肉在胫股关节中产生巨大的力量,从而影响关节软骨和半月板等组织的健康。有多种肌肉协调模式的行走是可能的,但各种肌肉协调对胫股接触力的影响尚不清楚。本研究的目的是确定各种肌肉协调对胫股接触力的影响。我们开发了一个带膝关节植入物行走的受试者肌肉骨骼模型。使用优化框架,我们计算了由肌肉协调产生的再现受试者行走动态的胫股力。我们进行了大量的优化,我们系统地改变了肌肉的协调,以确定对胫股力的影响。模型预测的最小肌肉激活产生的胫股力与早期站立时测量的体内力相匹配,但在站立后期比体内力更大。通过增加臀中肌、单关节髋屈肌和比目鱼肌的激活,以及减少腓肠肌和股直肌的激活,可以降低站立后期的胫股力峰值。这些结果表明,肌肉协调的再训练可以大大减少站立后期的胫股力。
Muscles induce large forces in the tibiofemoral joint during walking and thereby influence the health of tissues like articular cartilage and menisci. It is possible to walk with a wide variety of muscle coordination patterns, but the effect of varied muscle coordination on tibiofemoral contact forces remains unclear. The goal of this study was to determine the effect of varied muscle coordination on tibiofemoral contact forces. We developed a musculoskeletal model of a subject walking with an instrumented knee implant. Using an optimization framework, we calculated the tibiofemoral forces resulting from muscle coordination that reproduced the subject’s walking dynamics. We performed a large set of optimizations in which we systematically varied the coordination of muscles to determine the influence on tibiofemoral force. Model-predicted tibiofemoral forces arising with minimum muscle activation matched in vivo forces measured during early stance, but were greater than in vivo forces during late stance. Peak tibiofemoral forces during late stance could be reduced by increasing the activation of the gluteus medius, uniarticular hip flexors, and soleus, and by decreasing the activation of the gastrocnemius and rectus femoris. These results suggest that retraining of muscle coordination could substantially reduce tibiofemoral forces during late stance.
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