Novel mycosynthesis of Co3O4, CuO, Fe3O4, NiO, and ZnO nanoparticles by the endophytic Aspergillus terreus and evaluation of their antioxidant and antimicrobial activities
Novel mycosynthesis of Co3O4, CuO, Fe3O4, NiO, and ZnO nanoparticles by the endophytic Aspergillus terreus and evaluation of their antioxidant and antimicrobial activities
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内生土曲霉新型真菌合成 Co3O4、CuO、Fe3O4、NiO 和 ZnO 纳米颗粒及其抗氧化和抗菌活性评价
DOI：
10.1007/s00253-020-11046-4
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发表时间：
2021
影响因子：
5
通讯作者：
D. Abdou
中科院分区：
文献类型：
--
作者：
S. Mousa;El;Samar S. Mohamed;Mohamed A. Abo El;Adel A. Elmehlawy;D. Abdou
摘要：分离并筛选了几种内生真菌生物合成各种纳米粒子（NP）的能力，这是一种潜在的简单、环保且成本低廉的方法。在这些真菌中，一种名为 ORG-1 的有前途的分离株被发现能够合成五种不同的纳米颗粒类型：Co3O4NPs、CuONPs、Fe3O4NPs、NiONPs 和 ZnONPs。根据形态学和分子生物学研究，将ORG-1菌株鉴定为土曲霉(Aspergillus terreus)。这些纳米粒子的合成最初通过紫外-可见光谱进行监测，并通过傅里叶变换红外光谱进一步表征。 X射线衍射图揭示了它们的晶体结构。应用动态光散射分析来研究粒度分布和稳定性。透射电子显微镜研究表明了合成纳米颗粒的形态。此外，还评估了体外抗氧化和抗菌潜力的生物活性。 Co3O4NPs、CuONPs、Fe3O4NPs、NiONPs 和 ZnONPs 显示出良好的抗氧化活性，50% 抑制浓度分别为 85.44、96.74、102.41、87.41 和 108.67 μg mL−1。合成的纳米颗粒对多种植物和人类病原体表现出有效的抗菌活性。据我们所知，这是第一篇关于使用一种微生物菌株合成多种纳米颗粒的报道。这项研究表明，内生真菌作为新的替代平台，在合成具有良好活性的纳米颗粒方面具有非凡的潜力。要点•发现了一种有前景的内生真菌，用于合成五种不同类型的纳米颗粒。•研究了所有合成纳米颗粒的真菌合成和表征。•合成的纳米颗粒显示出良好的抗氧化和抗菌活性。
AbstractSeveral fungal endophytes were isolated and screened for their ability to biosynthesize a variety of nanoparticles (NPs), as a potentially simple and eco-friendly method with low cost. Among these fungi, a promising isolate named ORG-1 was found able to synthesize five different NPs types: Co3O4NPs, CuONPs, Fe3O4NPs, NiONPs, and ZnONPs. The ORG-1 strain was identified asAspergillus terreusaccording to the morphological and molecular studies. Synthesis of these NPs was initially monitored by UV–Vis spectroscopy and further characterized by Fourier transform infrared spectroscopy. X-ray diffraction patterns revealed their crystalline structure. Dynamic light scattering analysis was applied to study the particle size distribution and stability. Transmission electron microscope studies indicated the morphology of the synthesized NPs. Additionally, the biological activities of the in vitro antioxidant and antimicrobial potentials were evaluated. Co3O4NPs, CuONPs, Fe3O4NPs, NiONPs, and ZnONPs showed promising antioxidant activity with 50% inhibitory concentrations of 85.44, 96.74, 102.41, 87.41, and 108.67 μg mL−1, respectively. The synthesized NPs exhibited potent antimicrobial activities against several plant and human pathogens. To our knowledge, this is the first report on the use of one microbial strain for the synthesis of a variety of NPs. This study suggests endophytic fungi as new and alternate platforms with an exceptional potentiality for the synthesis of NPs with promising activities.Key points• Discovery of a promising endophytic fungus for synthesis of five different types of NPs.• Mycosynthesis and characterization of all the synthesized NPs were investigated.• The synthesized NPs showed promising antioxidant and antimicrobial activities.
影响因子：
15.1
作者：
Chatterjee, Shreosi;Mahanty, Shouvik;Das, Surajit
通讯作者：
Das, Surajit