PHOTOACOUSTIC ULTRASOUND
PHOTOACOUSTIC ULTRASOUND
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DOI：
10.1118/1.597367
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发表时间：
1994-01-01
期刊：
影响因子：
3.8
通讯作者：
KRUGER, RA
中科院分区：
文献类型：
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作者：
KRUGER, RA
通过记录短时间（类似于1 μ s）电磁能量脉冲在浑浊介质中被局部吸收时产生的光声脉冲，可以检测和定位三维的微分吸收。在体积为20x20x7.5 cm(3)的0.3% Liposyn (R)溶液（一种高散射介质）中，这些吸收位点的空间分辨率约为6 mm。使用氙灯照射Liposyn (R)溶液，输出标称1 μ s的宽带光脉冲。光声回波用聚焦超声换能器记录，调至0.5 MHz的标称频率。所证明的空间分辨率与换能器的预期超声特性一致。通过更短时间的辐射暴露和更高频率的换能器设计，可以期望提高空间分辨率。该技术可推广到任何电磁能量范围（包括长波长的微波），穿透介质并产生微分，区域吸收能量。
Differential absorption has been detected and localized in three-dimensions by recording the photoacoustic pulses that were produced when short-duration (similar to 1 mu s) pulses of electromagnetic energy were absorbed regionally within a turbid medium. These absorption sites were localized with a spatial resolution of similar to 6 mm within a 20X20X7.5-cm(3) volume of 0.3% Liposyn (R) solution, a highly scattering medium. A Xenon flashlamp, delivering a nominal 1 mu s pulse of broadband light, was used to irradiate the Liposyn (R) solution. Photoacoustic echoes were recorded with a focused, ultrasonic transducer, tuned to a nominal frequency of 0.5 MHz. The spatial resolution that was demonstrated is consistent with the expected ultrasonic properties of the transducer. Improved spatial resolution can be expected with shorter-duration radiation exposure and higher-frequency transducer designs. The technique is generalizable to any electromagnetic energy range (including long-wavelength microwaves) that penetrates the medium and produces differential, regional absorption of energy.