Current pharmacologic treatment for orthostatic hypotension

Current pharmacologic treatment for orthostatic hypotension
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DOI:
10.1007/s10286-007-1003-1
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发表时间:
2008-03-01
影响因子:
5.8
通讯作者:
Freeman, Roy
Freeman, Roy
中科院分区:
医学2区
文献类型:
--
作者:
Freeman, Roy

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体位性低血压的有效治疗与非药物和药物干预的联合使用。应告知患者潜在疾病的性质,并应消除直立性低血压的可逆原因。如果症状持续存在,则进行药物治疗。一线药物干预包括容量充盈联合α-肾上腺素受体激动剂。如果不成功,则存在具有不同作用机制的几种补充剂,其可提供累加效应。
Orthostatic hypotension is treated effectively with the combined use of non-pharmacological and pharmacological interventions. Patients should be counseled as to the nature of the underlying disorder and reversible causes of orthostatic hypotension should be removed. Should symptoms persist, pharmacological treatment is implemented. First line pharmacotherapeutic interventions include volume repletion in combination with alpha-adrenoreceptor agonists. If unsuccessful there are several supplementary agents with different mechanisms of action that may provide an additive effect.