Chemical wastes, children's health, and the Superfund Basic Research Program.
Chemical wastes, children's health, and the Superfund Basic Research Program.
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化学废物，儿童健康和超级基础研究计划。
DOI：
10.1289/ehp.99107423
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发表时间：
1999-06
影响因子：
10.4
通讯作者：
中科院分区：
文献类型：
--
作者：
在美国，有300万至400万儿童和青少年居住在联邦政府指定的超级基金危险废物处置场的1英里范围内，并有暴露于这些场所释放到空气，地下水，地表水和周围社区的化学毒物的风险。由于儿童的接触模式及其生物脆弱性，他们特别容易因接触环境中的化学毒物而受到健康伤害。由美国环境保护署资助、由国家环境卫生科学研究所指导的超级基金基础研究方案非常适合组织多学科研究，评估儿童接触来自危险废物处置场的危险化学品的模式;量化儿童对环境毒物的脆弱性;评估环境接触与儿科疾病之间的因果关系;从细胞和分子水平阐明儿童环境疾病的发病机制。
Three to 4 million children and adolescents in the United States live within 1 mile of a federally designated Superfund hazardous waste disposal site and are at risk of exposure to chemical toxicants released from these sites into air, groundwater, surface water, and surrounding communities. Because of their patterns of exposure and their biological vulnerability, children are uniquely susceptible to health injury resulting from exposures to chemical toxicants in the environment. The Superfund Basic Research Program, funded by the U.S. Environmental Protection Agency and directed by the National Institute of Environmental Health Sciences, is extremely well positioned to organize multidisciplinary research that will assess patterns of children's exposures to hazardous chemicals from hazardous waste disposal sites; quantify children's vulnerability to environmental toxicants; assess causal associations between environmental exposures and pediatric disease; and elucidate the mechanisms of environmental disease in children at the cellular and molecular level.