In vitro antimicrobial susceptibility of Brachyspira pilosicoli isolates from humans

In vitro antimicrobial susceptibility of Brachyspira pilosicoli isolates from humans
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DOI:
10.1128/aac.47.7.2354-2357.2003
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发表时间:
2003-07-01
影响因子:
4.9
通讯作者:
Riley, TV
Riley, TV
中科院分区:
医学2区
文献类型:
--
作者:
Brooke, CJ;Hampson, DJ;Riley, TV

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采用琼脂稀释法对厌氧肠道螺旋体的体外抗菌药物敏感性进行了研究。人(n = 123)和猪(n = 16)分离株对甲硝唑、头孢曲松、美罗培南、四环素、阿托沙星和氯霉素敏感;红霉素和环丙沙星无活性。对阿莫西林和克林霉素的耐药性各不相同。克拉维酸可恢复阿莫西林敏感性。
The in vitro antimicrobial susceptibility of the anaerobic intestinal spirochete Brachyspira pilosicoli was investigated by an agar dilution method. Human (n = 123) and porcine (n = 16) isolates were susceptible to metronidazole, ceftriaxone, meropenem, tetracycline, moxifloxacin, and chloramphenicol; erythromycin and ciprofloxacin were not active. Resistance to amoxicillin and clindamycin varied. Amoxicillin susceptibility was restored by clavulanic acid.