Disseminated Red Violaceous Papulonodular Lesions.
Disseminated Red Violaceous Papulonodular Lesions.
复制标题
播散性红色紫罗兰色丘疹结节性病变。
DOI：
10.1001/jamadermatol.2015.3949
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发表时间：
2016
期刊：
影响因子：
10.9
通讯作者：
F. Pérez
中科院分区：
文献类型：
--
作者：
R. Alarcón;F. Partarrieu;F. Pérez
Awoman in her 40spresented to the dermatology clinicwith a 6-month history of a generalized, asymptomatic, purplish-red papulonodular eruption. She reported that it began on her lower back and spread to her limbs during the next fewweeks. She denied any systemic symptoms.Hermedical historywas significant for addiction to freebase cocaine and volatile solvents during her adolescence, for which she had received adequate treatment. Shewasnot taking anymedication at the timeof consultation. Therewasnohistory of previouseruptions.Physical examination revealednumerous 10to25-mmredviolaceous,nontender, rubbery nodules andpapules togetherwith brownish-redpatches, all ofwhichhad somedegreeof scaling anda tendency to coalesce. The lesionsweredistributed across her face, trunk, andupper and lower limbsbilaterally (Figure, A andB). Palms, soles, scalp, genitalia, andmucosal surfaces were spared. Enlargement of lymph nodes and hepatosplenomegalywereabsent.Herneurological andmental stateexamination showednoabnormalities. Biopsy specimens from the forearm and back were obtained (Figure, C and D). Biopsy specimen obtained from the back D Biopsy specimen obtained from the forearm C Brownish-red confluent patches and plaques on the back B Purplish-red nodules on the right arm A
