Electrophysiological observations in patients with motor neuron disease receiving a thyrotropin releasing hormone analogue (RX77368).

Electrophysiological observations in patients with motor neuron disease receiving a thyrotropin releasing hormone analogue (RX77368).
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接受促甲状腺素释放激素类似物 (RX77368) 的运动神经元疾病患者的电生理学观察。

DOI:
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发表时间:
1987
影响因子:
11
通讯作者:
S. Lightman
S. Lightman
中科院分区:
医学1区
文献类型:
--
作者:
R. Guiloff;E. Stålberg;D. Eckland;S. Lightman

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29例运动神经元病患者接受促甲状腺激素释放激素类似物治疗后,肱二头肌的平均校正纤维密度、平均宏肌电幅和平均面积增加了25-30%。这些数据与药物对前角细胞的直接或间接作用一致。
Twenty nine patients with motor neuron disease receiving a thyrotropin releasing hormone analogue showed acute 25-30% increase in mean corrected fibre density and mean macro EMG median amplitude and area in brachial biceps muscle. The data are consistent with a direct or indirect action of the drug on anterior horn cells.