Comparative study of nasopharyngeal aspirate and nasal swab specimens for diagnosis of acute viral respiratory infection
Comparative study of nasopharyngeal aspirate and nasal swab specimens for diagnosis of acute viral respiratory infection
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DOI：
10.1128/jcm.01209-08
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发表时间：
2008-09-01
影响因子：
9.4
通讯作者：
Nelson, E. Anthony S.
中科院分区：
文献类型：
--
作者：
Sung, Rita Y. T.;Chan, Paul K. S.;Nelson, E. Anthony S.
采用免疫荧光试验、病毒培养和多重PCR方法对475例急性呼吸道感染住院患儿鼻咽吸出物（NPA）和鼻拭子（NS）进行流感病毒、副流感病毒、呼吸道合胞病毒和腺病毒的检测。NPA标本病毒检测的总体灵敏度高于NS标本。
Paired nasopharyngeal aspirate (NPA) and nasal swab (NS) samples from 475 children hospitalized for acute respiratory infection were studied for the detection of influenza virus, parainfluenza virus, respiratory syncytial virus, and adenovirus by immunofluorescence test, viral culture, and multiplex PCR assay. The overall sensitivity of viral detection with NPA specimens was higher than that obtained with NS specimens.