Regio- and Stereoselective Synthesis of β-Methylthio Vinyl Triflates.
Regio- and Stereoselective Synthesis of β-Methylthio Vinyl Triflates.
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DOI：
10.1021/acs.orglett.2c02880
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发表时间：
2022-09
期刊：
影响因子：
5.2
通讯作者：
Meizhong Tang;Y. Wei;Shenlin Huang;Lan-Gui Xie
中科院分区：
文献类型：
--
作者：
Meizhong Tang;Y. Wei;Shenlin Huang;Lan-Gui Xie
Vinyl triflates are commonly employed as electrophilic vinyl sources in complex synthesis. The triflation of enolates is commonly required for the preparation of vinyl triflates, generally under strongly basic conditions. Herein, the reaction between alkynes and dimethyl(methylthio)sulfonium trifluoromethanesulfonate is presented, which leads to the development of a facile synthesis of β-methylthio vinyl triflates in a chemo-, regio-, and stereoselective manner under neutral and extremely simple conditions.
