Superiority illusion arises from resting-state brain networks modulated by dopamine
Superiority illusion arises from resting-state brain networks modulated by dopamine
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DOI：
10.1073/pnas.1221681110
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发表时间：
2013-02
期刊：
影响因子：
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通讯作者：
M. Yamada;L. Uddin;Hidehiko Takahashi;Yasuyuki Kimura;K. Takahata;Ririko Kousa;Y. Ikoma;Yoko Eguchi;H. Takano;Hiroshi Ito;M. Higuchi;T. Suhara
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文献类型：
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作者：
M. Yamada;L. Uddin;Hidehiko Takahashi;Yasuyuki Kimura;K. Takahata;Ririko Kousa;Y. Ikoma;Yoko Eguchi;H. Takano;Hiroshi Ito;M. Higuchi;T. Suhara
大多数人认为自己比一般人优秀。这是一种被称为“优越感错觉”的认知偏见。这种幻觉帮助我们对未来抱有希望，并深深植根于人类进化的过程中。在这项研究中，我们使用静息状态功能MRI和PET检查了产生这种错觉的神经和分子系统的默认状态。抑制多巴胺能神经传递调节额叶皮层和纹状体之间的静息状态功能连接决定了个体的优越感水平。我们的发现有助于阐明人类思维的这一关键方面是如何在生物学上决定的，并确定治疗抑郁现实主义的潜在分子和神经靶点。
The majority of individuals evaluate themselves as superior to average. This is a cognitive bias known as the “superiority illusion.” This illusion helps us to have hope for the future and is deep-rooted in the process of human evolution. In this study, we examined the default states of neural and molecular systems that generate this illusion, using resting-state functional MRI and PET. Resting-state functional connectivity between the frontal cortex and striatum regulated by inhibitory dopaminergic neurotransmission determines individual levels of the superiority illusion. Our findings help elucidate how this key aspect of the human mind is biologically determined, and identify potential molecular and neural targets for treatment for depressive realism.