Clinical significance of serum carcinoembryonic antigen, carbohydrate antigen 19-9, and squamous cell carcinoma antigen levels in esophageal cancer patients
Clinical significance of serum carcinoembryonic antigen, carbohydrate antigen 19-9, and squamous cell carcinoma antigen levels in esophageal cancer patients
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DOI：
10.1007/s00268-004-6865-y
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发表时间：
2004-07-01
影响因子：
2.6
通讯作者：
Hatakeyama, K
中科院分区：
文献类型：
--
作者：
Kosugi, S;Nishimaki, T;Hatakeyama, K
评估血清癌胚抗原（CEA）、碳水化合物抗原（CA）19-9和鳞状细胞癌（SCC）抗原水平，以确定其水平是否可用于术前食管癌分期和预测食管切除术后患者生存率。因此，在不可切除的食管癌患者（n=63）和因可切除疾病接受食管切除术的患者（n=267）中，研究了其血清阳性与可切除性、肿瘤进展的临床病理学参数和治疗结局的相关性。血清SCC抗原水平异常升高与可切除性显著相关（p
Serum carcinoembryonic antigen (CEA), carbohydrate antigen (CA) 19-9, and squamous cell carcinoma (SCC) antigen levels were assessed to determine if their levels are useful for staging esophageal cancer preoperatively and for predicting patient survival after esophagectomy. Hence their seropositivity was investigated for a correlation with resectability, clinicopathologic parameters of tumor progression, and treatment outcomes in patients with unresectable esophageal cancer (n=63) and those undergoing esophagectomy for resectable disease (n=267). Abnormal elevation of serum SCC antigen levels showed a significant correlation with resectability (p