Two different subcortical language networks supporting distinct Japanese orthographies: morphograms and phonograms
Two different subcortical language networks supporting distinct Japanese orthographies: morphograms and phonograms
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DOI：
10.1007/s00429-022-02454-5
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发表时间：
2022-01
影响因子：
3.1
通讯作者：
Sho Tamai;M. Kinoshita;Riho Nakajima;Hirokazu Okita;M. Nakada
中科院分区：
文献类型：
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作者：
Sho Tamai;M. Kinoshita;Riho Nakajima;Hirokazu Okita;M. Nakada
世界各地的语言系统都是基于形态图或表音文字，但日语是独一无二的，它使用了汉字（形态图）和假名（表音文字）字符的复杂组合。与阅读相关的白色物质网络以前已经被研究过，但仍然没有完全理解。在这项研究中，我们在局部麻醉下进行了术中语言映射，并对53例接受清醒开颅手术切除优势颞叶或顶叶脑胶质瘤的连续患者进行了术后语言评估。检查了6例术中直接电刺激（DES）引起的阅读障碍，所有病例均在DES期间出现短暂的汉字或假名阅读障碍症状。我们研究了位于四个白色束附近的术中阳性标测点：弓状束、后上级纵束、额枕下纵束和下纵束（ILF）。汉字阅读障碍的术中DES分布与ILF的前下侧特别相关。另一方面，与假名阅读障碍相关的DES点位于由这四条神经束组成的复合体的后上侧。这些结果表明存在特定的非干扰网络，有助于阅读形态图和表音图的过程。
Language systems worldwide are based on either morphograms or phonograms, but Japanese is unique in that uses a complicated combination of kanji (morphogram) and kana (phonogram) characters. The white matter networks associated with reading have been investigated previously but remain incompletely understood. In this study, we performed intraoperative language mapping under local anesthesia and postoperative language assessments of 53 consecutive patients who underwent awake craniotomy for surgical resection of cerebral glioma within the dominant temporal or parietal lobe. Six cases showing intraoperative dyslexia elicited by direct electrical stimulation (DES) were examined, and all cases showed transient symptoms of kanji or kana dyslexia during DES. We investigated the intraoperative positive mapping points localized near four white matter bundles: the arcuate fascicle, posterior superior longitudinal fascicle, inferior fronto-occipital longitudinal fascicle, and inferior longitudinal fascicle (ILF). The intraoperative DES distributions for kanji dyslexia were especially associated with the anterior-inferior side of the ILF. On the other hand, the DES points associated with kana dyslexia were localized on the posterior-superior side of the complex composed of these four tracts. These results suggest the presence of specific non-interfering networks that subserve the processes of reading morphograms and phonograms.