Normative blood pressure data in the early neonatal period
Normative blood pressure data in the early neonatal period
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DOI：
10.1007/s00467-007-0480-8
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发表时间：
2007-09-01
影响因子：
3
通讯作者：
Falk, Michael C.
中科院分区：
文献类型：
--
作者：
Kent, Alison L.;Kecskes, Zsuzsoka;Falk, Michael C.
在过去的三十年里，出生体重一直有增加的时间趋势。出生体重的增加可能导致了新生儿血压的增加。新生儿高血压正变得越来越普遍，特别是在新生儿重症监护病房幸存者中。目前的标准值需要帮助诊断和适当处理新生儿低血压和高血压。这项研究的目的是确定健康足月新生儿的正常血压读数。研究对象为2003年8月至2005年8月在产后病房出生的足月新生儿。排除标准包括患有先兆子痫的母亲的婴儿、任何原因的高血压、妊娠期糖尿病、1型糖尿病和非法药物使用、婴儿先天性或染色体异常、进入新生儿重症监护病房或可能的败血症。在登记的406名婴儿中，有218名是男性。出生第1天的平均血压分别为65 mm Hg、45 mm Hg和48 mm Hg。在第4天，这些数值分别增加到70、46和54毫米汞。从出生第1天到第2天，血压显著升高。血压读数在出生体重或身长方面没有显著差异。性别之间唯一的显著差异是男孩在第二天的平均和舒张压较低。这项研究提供了健康足月新生儿目前的标准血压读数，可以用来评估足月新生儿的低血压和高血压。从之前的研究中没有发现血压增加。
There has been a temporal trend towards increased birth weight over the past three decades. This increase in birth weight may have resulted in an increase in neonatal blood pressure. Neonatal hypertension is becoming more common, especially in neonatal intensive care unit survivors. Current normative values are required to assist in diagnosis and appropriate management of neonatal hypotension and hypertension. The objective of this study was to determine normative blood pressure readings in healthy term neonates. Term neonates from the postnatal ward were enrolled from August 2003 to August 2005. Exclusion criteria included infants of mothers with preeclampsia, hypertension of any cause, gestational diabetes, type 1 diabetes mellitus and illicit substance use, infant congenital or chromosomal anomaly, admission to the neonatal intensive care unit or possible sepsis. Of the 406 infants enrolled, 218 were male. The median systolic, diastolic and mean blood pressures on day 1 of life were 65 mmHg, 45 mmHg, and 48 mmHg, respectively. On day 4, these values had increased to 70 mmHg, 46 mmHg and 54 mmHg. There was a significant elevation in blood pressure from day 1 to day 2 of life. There was no significant difference in blood pressure readings with respect to birth weight or length. The only significant difference between the sexes was a lower mean and diastolic pressure on day 2 in boys. This study has provided current normative blood pressure readings of healthy term neonates that can be used to assess both hypotension and hypertension in the term neonate. No increase in blood pressure was noted from previous studies.