Reading and Subcortical Auditory Function
Reading and Subcortical Auditory Function
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DOI：
10.1093/cercor/bhp024
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发表时间：
2009-11-01
期刊：
影响因子：
3.7
通讯作者：
Kraus, Nina
中科院分区：
文献类型：
--
作者：
Banai, Karen;Hornickel, Jane;Kraus, Nina
虽然人们普遍认为语音加工缺陷是阅读能力差的主要原因，但语音加工的神经起源还没有得到很好的理解。我们现在表明，第一次，语音解码，测量与测试的单非字阅读，是显着相关的皮层下听觉处理的时间，也在较小程度上，与鲁棒性的皮层下代表的谐波内容的语音，但不与音高编码。我们观察到的阅读和皮层下处理之间的关系是沿着一个连续体的，一端是差的阅读者，另一端是好的阅读者。这些数据表明，阅读技能可能取决于完整的皮层下听觉机制，并与语音的声学特征的皮层下表征可能在正常阅读以及阅读障碍的发展中发挥作用的想法是一致的。这些数据建立了皮层下听觉功能和阅读之间的重要联系，从而有助于理解阅读的生物学基础。在更普遍的层面上，这些发现是第一个建立皮层下感觉功能和特定认知技能（阅读）之间直接关系的发现。我们认为，皮质和皮质下功能之间的这种关系可以形成在发展过程中的离皮质途径，这种皮质-皮质下的链接可能有助于语音处理赤字的穷人的读者。
Although it is largely agreed that phonological processing deficits are a major cause of poor reading, the neural origins of phonological processing are not well understood. We now show, for the first time, that phonological decoding, measured with a test of single-nonword reading, is significantly correlated with the timing of subcortical auditory processing and also, to a lesser extent, with the robustness of subcortical representation of the harmonic content of speech, but not with pitch encoding. The relationships we observe between reading and subcortical processing fall along a continuum, with poor readers at one end and good readers at the other. These data suggest that reading skill may depend on the integrity of subcortical auditory mechanisms and are consistent with the idea that subcortical representation of the acoustic features of speech may play a role in normal reading as well as in the development of reading disorders. These data establish a significant link between subcortical auditory function and reading, thereby contributing to the understanding of the biological bases of reading. At a more general level, these findings are among the first to establish a direct relationship between subcortical sensory function and a specific cognitive skill (reading). We argue that this relationship between cortical and subcortical function could be shaped during development by the corticofugal pathway and that this cortical-subcortical link could contribute to the phonological processing deficits experienced by poor readers.