Cement dust exposure and ventilatory function impairment:: An exposure-response study
Cement dust exposure and ventilatory function impairment:: An exposure-response study
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DOI：
10.1097/01.jom.0000131787.02250.79
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发表时间：
2004-07-01
影响因子：
3.2
通讯作者：
Mashalla, Y
中科院分区：
文献类型：
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作者：
Mwaiselage, J;Bråtveit, M;Mashalla, Y
我们调查了累计总水泥粉尘暴露和通风功能损害在坦桑尼亚波特兰水泥厂。126名生产工人全部受到感染。对照组包括所有88名维修工人和32名随机选择的办公室工作人员。经年龄、工作时间、身高和工作年限调整后，暴露工人的用力肺活量（FVC）、1秒用力呼气量（FEV1）、呼气峰流速（PEF）、FEV1/FVC、FVC%、FEV1%和PEF%显著低于对照组。累积总粉尘暴露与植被覆盖度降低、1秒用力呼气量和呼气峰值流速（根据年龄、身高和包年调整）显著相关。与低于100 mg/m(3)年相比，累计总粉尘暴露量超过300 mg/m(3)年与发生气流限制的风险增加显著相关（优势比= 9.9）。目前总水泥粉尘的职业接触限值（10 mg/m(3)）似乎过高，无法防止对水泥工人的呼吸健康造成影响。
We investigated cumulative total cement dust exposure and ventilatory function impairment at a Portland cement factory in Tanzania. All 126 production workers were exposed. The control group comprised all 88 maintenance workers and 32 randomly chosen office workers. Exposed workers had significantly lower forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), peak expiratory flow rate (PEF), FEV1/FVC, FVC%, FEV1% and PEF%, than controls adjusted for age, duration of employment, height, and pack-years. Cumulative total dust exposure was significantly associated with reduced FVC, forced expiratory volume in 1 second, and peak expiratory flow rate adjusted for age, height and pack-years. Cumulative total dust exposure more than 300 mg/m(3) year versus lower than 100 mg/m(3) years was significantly associated with increased risk of developing airflow limitation (odds ratio = 9.9). The current occupational exposure limit for total cement dust (10 mg/m(3)) appears to be too high to prevent respiratory health effects among cement workers.