Lithiation-induced migrations from nitrogen to carbon in terminal aziridines
Lithiation-induced migrations from nitrogen to carbon in terminal aziridines
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DOI：
10.1002/anie.200604920
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发表时间：
2007-01-01
影响因子：
16.6
通讯作者：
Ward, John G.
中科院分区：
文献类型：
--
作者：
Hodgson, David M.;Humphreys, Philip G.;Ward, John G.
受益于去保护：2,2,6,6-四甲基哌啶酸锂诱导N-Boc或n -膦酸末端的氮基进行区域和立体选择性的n -到- c迁移，得到有合成价值的反式氮基酰基酯和反式氮基膦酸盐。©2007 Wiley-VCH Verlag GmbH and Co. KGaA。
(Chemical Equation Presented) Benefiting from deprotection: Lithium 2,2,6,6-tetramethylpiperidide induces N-Boc or N-phosphonate terminal aziridines to undergo regio- and stereoselective N-to-C migration of the protecting group, giving synthetically valuable trans-aziridinylesters and trans- aziridinylphosphonates. © 2007 Wiley-VCH Verlag GmbH and Co. KGaA.