Prevalence of HIV and syphilis infection among men who have sex with men in China: a meta-analysis.
Prevalence of HIV and syphilis infection among men who have sex with men in China: a meta-analysis.
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中国男男性行为者艾滋病毒和梅毒感染流行情况的荟萃分析
DOI：
10.1155/2014/620431
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发表时间：
2014
影响因子：
--
通讯作者：
Gao G
中科院分区：
文献类型：
--
作者：
Zhou Y;Li D;Lu D;Ruan Y;Qi X;Gao G
目标.了解中国男男性行为人群HIV和梅毒的最新流行情况。方法.对通过PubMed、CNKI和万方检索的2009年1月1日至2013年4月11日期间发表的研究进行了荟萃分析。结果共纳入84篇符合条件的中文或英文文献。中国男男性行为人群HIV和梅毒合并感染率分别为6.5%和11.2%。亚组分析显示，经济欠发达城市HIV感染率高于经济发达城市（7.5%比6.1%，P < 0.05）。相比之下，梅毒感染率在欠发达城市低于发达城市（8.6%对15.1%）。样本量小于500的研究中，HIV和梅毒感染的患病率低于样本量大于500的研究（HIV分别为5.9%和7.2%;梅毒分别为11.0%和11.5%）。结论. HIV和梅毒感染在我国MSM人群中普遍存在。发展中城市和发达城市之间艾滋病毒和梅毒感染的流行率不同，这突出表明需要根据经济条件制定有针对性的预防战略。
Objectives. To figure out the most current prevalence of HIV and syphilis in MSM in China. Methods. A meta-analysis was conducted on the studies searched through PubMed, CNKI, and Wanfang published between 1 January 2009 and 11 April 2013. Results. Eighty-four eligible studies, either in Chinese or in English, were included in this review. The pooled prevalence of HIV and syphilis infection in MSM in China was 6.5% and 11.2%, respectively. The subgroup analyses indicated that the prevalence of HIV infection was higher in the economically less developed cities than that in the developed cities (7.5% versus 6.1%, P < 0.05). In contrast, the prevalence of syphilis infection was lower in less developed cities than in developed cities (8.6% versus 15.1%). Studies with a sample size smaller than 500 had a lower prevalence of HIV and syphilis infection than those with a sample size greater than 500 (5.9% versus 7.2% for HIV; 11.0% versus 11.5% for syphilis, respectively). Conclusions. HIV and syphilis infection are prevalent in MSM in China. The different prevalence of HIV and syphilis infection between developing and developed cities underscores the need to target prevention strategies based on economic conditions.