Herpesvirus interference with virus-specific antibodies: Bridging antibodies, internalizing antibodies, and hiding from antibodies
Herpesvirus interference with virus-specific antibodies: Bridging antibodies, internalizing antibodies, and hiding from antibodies
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DOI：
10.1016/j.vetmic.2005.11.003
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发表时间：
2006-03-31
影响因子：
3.3
通讯作者：
Nauwynck, HJ
中科院分区：
文献类型：
--
作者：
Favoreel, HW;Van Minnebruggen, G;Nauwynck, HJ
疱疹病毒已经开发出不同的工具来阻止有效的抗体依赖的病毒粒子的中和和裂解，以及消除受感染的细胞。这篇综述将简要总结这些工具的不同，包括(I)病毒Fc受体和由此产生的抗体桥接过程，(Ii)单个病毒蛋白和聚集的抗体-抗原复合体从受感染细胞的质膜内化，以及(Iii)病毒颗粒直接排出到抗体难以进入的密切细胞-细胞接触部位。(C)2005 Elsevier B.V.保留所有权利。
Herpesviruses have developed different tools to thwart efficient antibody-dependent neutralisation and lysis of virions and elimination of infected cells. This overview will briefly summarize different of these tools, including (i) viral Fc receptors and the resulting process of antibody bridging, (ii) internalization of individual viral proteins and clustered antibody-antigen complexes from the plasma membrane of infected cells, and (iii) directed egress of virus particles to sites of intimate cell-cell contact that are difficult to access for antibodies. (c) 2005 Elsevier B.V. All rights reserved.