An age-structured model for the AIDS epidemic
An age-structured model for the AIDS epidemic
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DOI：
10.1016/s0377-2217(99)00288-x
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发表时间：
2000-07-01
影响因子：
6.4
通讯作者：
Williams, J
中科院分区：
文献类型：
--
作者：
Griffiths, J;Lowrie, D;Williams, J
最近的研究表明，导致艾滋病的病毒艾滋病毒的潜伏期显然与年龄有关。本文描述了一个模型，该模型以同性恋人群的年龄概况作为输入，并输出易感者、艾滋病毒感染者和艾滋病病例随时间变化的概况。在可能的情况下，我们与欧洲的数据进行了比较，特别是来自大伦敦地区和法国的数据。该模型可以进行调整，以纳入政府资助的艾滋病预防计划等运动的影响。特别是，可以确定需要针对哪些年龄组才能使活动最有效。同样，该模型可能有助于制定与年龄相关的治疗方案。 (C) 2000 Elsevier Science B.V. 保留所有权利。
Recent research has shown that the incubation period of HIV, the virus that leads to AIDS, is clearly age dependent. This paper describes a model that takes as input an age-profile from the homosexual population and outputs the changing profiles over time of the susceptible, HIV infectives and AIDS cases. Where possible comparisons have been made with European data, in particular from the Greater London region and France. The model can be adapted to incorporate the effects of campaigns such as government-sponsored AIDS prevention programmes. In particular, it is possible to determine which age-groups need to be targeted for a campaign to be most effective. Similarly, the model could be helpful in mounting age-dependent treatment programmes. (C) 2000 Elsevier Science B.V. All rights reserved.