Support vector machine learning-based cerebral blood flow quantification for arterial spin labeling MRI.

Support vector machine learning-based cerebral blood flow quantification for arterial spin labeling MRI.
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DOI:
10.1002/hbm.22445
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发表时间:
2014-07
影响因子:
4.8
通讯作者:
Wang, Ze
Wang, Ze
中科院分区:
医学2区
文献类型:
--
作者:
Wang, Ze

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To develop a multivariate machine learning classification-based cerebral blood flow (CBF) quantification method for arterial spin labeling (ASL) perfusion MRI. The label and control images of ASL MRI were separated using a machine-learning algorithm, the support vector machine (SVM). The perfusion-weighted image was subsequently extracted from the multivariate (all voxels) SVM classifier. Using the same preprocessing steps, the proposed method was compared to standard ASL CBF quantification method using synthetic data and in-vivo ASL images. As compared to the conventional univariate approach, the proposed ASL CBF quantification method significantly improved spatial signal-to-noise-ratio (SNR) and image appearance of ASL CBF images. the multivariate machine learning-based classification is useful for ASL CBF quantification.
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