EABR measurements during cochlear implantation in one-year-old, infant, child, adult, and elderly patients
EABR measurements during cochlear implantation in one-year-old, infant, child, adult, and elderly patients
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一岁儿童、婴儿、儿童、成人和老年患者人工耳蜗植入期间的 EABR 测量
DOI：
10.1080/00016489.2020.1826576
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发表时间：
2021
影响因子：
1.4
通讯作者：
Kaga Kimitaka
中科院分区：
文献类型：
--
作者：
Enomoto Chieko;Minami Shujiro;Kaga Kimitaka
背景电诱发耳蜗内听觉脑干反应（eABR）用于评估脑干成熟度或衰老变化的临床应用尚未得到很好的研究。目的/目的我们比较一岁儿童、婴儿、儿童、成人和老年人术中 eABR 测量的 eV 潜伏期，目的是调查脑干听觉通路因发育和衰老而发生的变化。材料和方法我们研究了 58 只耳朵2013 年至 2019 年间，有 51 名患者使用 MED-EL 的 Concerto 或 Synchrony 植入物（配有 Flex28 或 Flex 软电极）接受了人工耳蜗植入。在人工耳蜗植入期间记录 EABR。 MED-EL Maestro 以 1000、800 和 600 cu 的刺激水平将刺激传递到顶端、中间和基底转动电极，脉冲宽度为 30 µs。结果在乳突和颈背安装的电极记录的 eABR 中，每个刺激水平内各年龄组之间的潜伏期没有差异。结论和意义 ABR 潜伏期不受一岁后发育和年龄增长的影响。脑干听觉通路。我们的研究将有助于作为对照，识别耳蜗畸形、耳蜗神经缺陷或听神经病患者的异常 eABR 波配置，无论其年龄如何。
BackgroundClinical application of electrically-evoked intracochlear auditory brainstem responses (eABRs) for evaluation of brainstem maturity or aging changes has not been well investigated.Aim/objectiveWe compare the eV latencies of intraoperative eABR measurements in one-year-olds, infants, children, adults, and the elderly, with the goal of investigating the changes in the brainstem auditory pathway due to development and aging.Materials and methodsWe studied 58 ears of 51 patients who underwent cochlear implantation between 2013 and 2019 using MED-EL’s Concerto or Synchrony implants with Flex28 or Flex soft electrodes. EABRs were recorded during cochlear implantation. The stimuli were delivered by the MED-EL Maestro to the apical, middle, and basal turn electrodes at stimulus levels 1000, 800, and 600 cu, with a pulse width of 30 µs.ResultsIn eABRs recorded from electrodes installed at both the mastoid and nape, there was no difference in latency between age groups within each stimulus level.Conclusion and significanceABR latency was not affected by development after age one and aging of the brainstem auditory pathway. Our study will be useful as a control in identifying abnormal eABR wave configurations in patients with cochlear malformations, cochlear nerve deficiencies, or auditory neuropathy, regardless of age.