Mediation of pathogen resistance by exudation of antimicrobials from roots (Retracted Article)
Mediation of pathogen resistance by exudation of antimicrobials from roots (Retracted Article)
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DOI：
10.1038/nature03356
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发表时间：
2005-03-10
期刊：
影响因子：
64.8
通讯作者：
Vivanco, JM
中科院分区：
文献类型：
--
作者：
Bais, HP;Prithiviraj, B;Vivanco, JM
大多数植物物种对大多数潜在的病原体具有抗性。目前尚不清楚为什么大多数植物-微生物相互作用不会导致疾病，尽管最近的研究表明这种基本的抗病性是多因素的（1，2）。在这里，我们表明，分泌的根来源的抗微生物代谢产物的拟南芥赋予组织特异性的阻力，以广泛的细菌病原体。然而，对这些化合物具有至少部分抗性并且能够阻断其合成/分泌的假单胞菌菌株能够感染根部并引起疾病。我们还表明，这种P. pastingae菌株阻止抗菌渗出的能力是依赖于III型分泌系统。
Most plant species are resistant to most potential pathogens. It is not known why most plant - microbe interactions do not lead to disease, although recent work indicates that this basic disease resistance is multi-factorial(1,2). Here we show that the exudation of root-derived antimicrobial metabolites by Arabidopsis thaliana confers tissue-specific resistance to a wide range of bacterial pathogens. However, a Pseudomonas syringae strain that is both at least partly resistant to these compounds and capable of blocking their synthesis/exudation is able to infect the roots and cause disease. We also show that the ability of this P. syringae strain to block antimicrobial exudation is dependent on the type III secretory system.