Dopaminergic system as the mechanism underlying personality in a beetle
Dopaminergic system as the mechanism underlying personality in a beetle
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DOI：
10.1016/j.jinsphys.2012.02.011
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发表时间：
2012-05-01
影响因子：
2.2
通讯作者：
Miyatake, Takahisa
中科院分区：
文献类型：
--
作者：
Nakayama, Satoshi;Sasaki, Ken;Miyatake, Takahisa
在许多动物物种中，个体表现出“个性”，即不同时间、不同情况和/或不同背景下行为的一致差异。先前的工作已经揭示了迷惑的粉甲虫的紧张性不动强度和行走活动水平之间的负遗传相关性，从而表明这些甲虫在与活动相关的特征中表现出个性。本研究调查了这种相关性背后的机制。我们使用来自两个菌株的个体，通过人工发散选择建立，用于紧张性不动的持续时间。“长”(L)品系表现出较高的紧张性静止频率和较长的持续时间以及较低的活性水平，而“短”(S)品系表现出较低的紧张性静止频率和较短的紧张性静止时间和较高的活动水平。我们发现，咖啡因可以改变紧张性静止的持续时间和活动水平；饲喂咖啡因的L菌株表现出紧张性静止的持续时间缩短和活动水平增加。我们还发现，L品系的脑多巴胺水平低于S品系。因此，这项研究表明，多巴胺能系统在控制该物种紧张性静止和活动水平之间的遗传相关性方面发挥着重要作用。(C)2012爱思唯尔有限公司。保留所有权利。
Individuals in many animal species exhibit 'personality,' consistent differences in behaviour across time, situations and/or contexts. Previous work has revealed a negative genetic correlation between intensity of tonic immobility and walking activity levels in the confused flour beetle, Tribolium confusum, thus suggesting these beetles exhibit personality in activity-related traits. The present study investigated the mechanism underlying this correlation. We used individuals derived from two strains established via artificial divergent selection for duration of tonic immobility. "Long" (L) strains exhibited higher frequencies and longer durations of tonic immobility, and lower activity levels, while "Short" (S) strains exhibited lower frequencies and shorter durations of tonic immobility and higher activity levels. We found that the duration of tonic immobility, and activity level, could be altered by caffeine administration; L strains fed with caffeine exhibited decreased durations of tonic immobility and increased activity levels. We also found that brain dopamine levels were lower in L strains than in S strains. Consequently, this study demonstrates that the dopaminergic system plays an important part in controlling the genetic correlation between tonic immobility and activity levels in this species. (C) 2012 Elsevier Ltd. All rights reserved.