SHORT-TERM IMMOBILIZATION HAS A MINIMAL EFFECT ON THE STRENGTH AND FATIGABILITY OF A HUMAN HAND MUSCLE
SHORT-TERM IMMOBILIZATION HAS A MINIMAL EFFECT ON THE STRENGTH AND FATIGABILITY OF A HUMAN HAND MUSCLE
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DOI：
10.1152/jappl.1995.78.3.847
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发表时间：
1995-03-01
影响因子：
3.3
通讯作者：
ENOKA, RM
中科院分区：
文献类型：
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作者：
FUGLEVAND, AJ;BILODEAU, M;ENOKA, RM
本研究的目的是确定通常在废用肌肉中观察到的疲劳性降低与对神经肌肉传播损伤的抵抗力提高之间的关联。在制动前、制动中和制动后3周（n = 9）或5周（n = 2），测量了受试者第一骨间背侧肌在35%最大随意收缩（MVC）力下持续等长收缩的耐力时间和疲劳引起的诱发复合肌肉动作电位（M波）的变化。制动程序造成的慢性肌电图（EMG）活动（控制值的4%）的第一背侧骨间肌的大幅下降。耐力时间被认为是显着相关的M波振幅的维持在疲劳任务。然而，这些变量都没有显着影响固定。此外，制动没有显着影响的MVC力和肌电图或抽搐收缩时间或MVC力和肌电图，M波持续时间，抽搐幅度和收缩时间的疲劳后变化的prefatigue值。在非疲劳肌肉中，制动确实引起了抽搐力的增加（153%）和M波振幅的降低（67%）。因此，健康的第一骨间背侧肌在制动减少其使用3-5周后，通常会抵抗适应。
The purpose of this study was to determine the association between reduced fatigability typically observed in disused muscle and an improved resistance to the impairment of neuromuscular propagation. Endurance time of an isometric contraction sustained at 35% of maximum voluntary contraction (MVC) force and the fatigue-induced change in the evoked compound muscle action potential (M wave) were measured in the first dorsal interosseus muscle of human subjects before, during, and after 3 (n = 9) or 5 wk (n = 2) of immobilization. The immobilization procedure caused a substantial decline in the chronic electromyographic (EMG) activity (to 4% of control value) of the first dorsal interosseus muscle. Endurance time was found to be significantly correlated to the maintenance of M-wave amplitude during the fatigue task. However, neither of these variables was significantly affected by immobilization. Also, immobilization had no significant effect on the prefatigue values of MVC force and EMG or twitch contraction time or on the postfatigue changes in MVC force and EMG, M wave duration, twitch amplitude, and contraction time. In the unfatigued muscle, immobilization did cause an increase in twitch force (153%) and a decrease in M-wave amplitude (67%). It appears, therefore, that a healthy first dorsal interosseus muscle is generally resistant to adaptation when its use has been reduced for 3-5 wk by immobilization.