Food groups associated with measured net acid excretion in community-dwelling older adults.
Food groups associated with measured net acid excretion in community-dwelling older adults.
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DOI：
10.1038/ejcn.2016.195
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发表时间：
2017-03
影响因子：
4.7
通讯作者：
Dawson-Hughes B
中科院分区：
文献类型：
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作者：
Shea MK;Gilhooly CH;Dawson-Hughes B
产酸饮食与不良健康状况有关。膳食酸负荷可以从膳食摄入量数据估计，但现有的方法需要全面的膳食评估。我们试图确定一种更简单的方法来估计24小时尿净酸排泄量（NAE），这是一种有效的内源性净酸产生量测量方法，使用社区居住的老年人通过两种不同方法获得的水果，蔬菜（酸中和食物），谷物和/或蛋白质（产酸食物）的自我报告摄入量。使用不需要全面饮食评估的方法确定与NAE相关的食物组可能具有广泛的临床应用。使用广泛使用的食物频率问卷（研究A，n=162，63±8岁）估计水果、蔬菜、蛋白质和谷物/天。使用方差分析分析不同NAE类别（<5，≥ 5至<15，≥ 15至<50，≥50毫当量（mEq）/天）的摄入量差异。第二项研究证实了这一发现，该研究使用更详细的记录辅助24小时回忆来估计饮食摄入量（研究B，n=232，67±6岁）。在两项研究中，水果摄入量与NAE显著相关。在研究A中，每增加一个分类NAE，水果摄入量降低9%（非标准化beta=-0.21，p = 0.01），在研究B中，每增加一个分类NAE，水果摄入量降低7%（非标准化beta=-0.18;p=0.02）。仅在研究B中，谷物摄入量与NAE呈正相关（未标准化β =+0.14;p=0.01）。在两项研究中，蔬菜和蛋白质摄入量与NAE无关。水果摄入量和NAE之间的负相关表明，自我报告的水果摄入量低可能是老年人产酸饮食的一个指标。
Acid-producing diets have been associated with adverse health conditions. Dietary acid load can be estimated from dietary intake data, but the available methods require a full dietary assessment. We sought to identify a simpler means to estimate 24-hour urinary net acid excretion (NAE), a robust measure of net endogenous acid production, using self-reported intakes of fruits, vegetables (acid-neutralizing foods), grain and/or protein (acid-producing foods)acquired by two different methods in community-dwelling older adults. Identifying food groups associated with NAE using a method not requiring a full diet assessment could have a broad clinical application. Fruit, vegetable, protein, and grain servings/day were estimated with a widely-used food frequency questionnaire (study A, n=162, 63±8 years). Differences in their intakes across NAE categories (<5, ≥5to <15, ≥15to <50, ≥50 milliequivalents (mEq)/day) were analyzed using analysis of variance. The findings were verified in a second study which estimated dietary intakes using a more detailed record-assisted 24- hour recall (study B, n=232, 67±6 years). Fruit intake was significantly associated with NAE in both studies. In study A, fruit intake was 9% lower with each categorical NAE increase (unstandardized beta=-0.21,p=0.01) and 7% lower with each categorical NAE increase in study B (unstandardized beta=-0.18;p=0.02). Grain intake was positively associated with NAE in study B only (unstandardized beta=+0.14;p=0.01). Vegetable and protein intake were not associated with NAE in either study. The inverse association between fruit intake and NAE suggests low self-reported fruit intake may be an indicator of acid-producing diets in older adults.