PRESENCE OF TYPE-3 COLLAGEN IN GUINEA-PIG DERMAL SCAR
PRESENCE OF TYPE-3 COLLAGEN IN GUINEA-PIG DERMAL SCAR
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DOI：
10.1042/bj1570263
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发表时间：
1976-01-01
影响因子：
4.1
通讯作者：
BAILEY, AJ
中科院分区：
文献类型：
--
作者：
BARNES, MJ;MORTON, LF;BAILEY, AJ
豚鼠真皮疤痕含有III型胶原蛋白，从凝胶电泳图的光密度分析来看，其浓度高于周围真皮。这一发现与新形成的真皮伤口组织的胚胎性质一致，反映在胶原蛋白赖氨酸的羟基化增加和二羟基赖氨酸正亮氨酸（还原后）作为主要交联的存在。
Guinea-pig dermal scar contained type III collagen, and, from densitometric analysis of gel electrophoretograms, it had a higher concentration than the surrounding dermis. This finding is consistent with the embryonic nature of newly formed dermal wound tissue, reflected in increased hydroxylation of collagen lysine and the presence of dihydroxylysinonorleucine (after reduction) as the major cross-link.